Tumor necrosis factor alpha mediates neuromuscular synapse elimination
نویسندگان
چکیده
منابع مشابه
Evaluation of Tumor Necrosis Factor Alpha Polymorphism Frequencies in Endometriosis
Background The pro-inflammatory cytokine, tumor necrosis factor-alpha (TNF-α), is a pathogenic element for a number of disorders. Previous studies have reported that the -1031 T/C and -238 G/A polymorphisms in the promoter region of the TNF-α gene are important factors in reproductive-related disorders. One of the most common gynecological diseases of women during the reproductive years is endo...
متن کاملExpression of tumor necrosis factor-alpha--converting enzyme and tumor necrosis factor-alpha in human myocarditis.
OBJECTIVES We determined whether tumor necrosis factor-alpha-converting enzyme (TACE) is expressed with tumor necrosis factor-alpha (TNF-alpha) in myocarditis. BACKGROUND Tumor necrosis factor-alpha-converting enzyme, which has recently been identified as belonging to the family of metalloproteinase disintegrin proteins, is responsible for the conversion of TNF-alpha precursor to its mature f...
متن کاملEndometriosis Classification and The Role of Tumor Necrosis Factor-Alpha Polymorphisms as A Therapeutic Target
In the recent original research published on International Journal of Fertility and Sterility the association between tumor necrosis factor-alpha (TNF-α) genetic polymorphisms and endometriosis in 150 Iranian patients suffered this disease. The authors notably found a lower frequency of TNF-α -863C/A allele A among the affected patients in comparison with healthy women, although this difference...
متن کاملevaluation of tumor necrosis factor alpha polymorphism frequencies in endometriosis
background: the pro-inflammatory cytokine, tumor necrosis factor-alpha (tnf-α), is a pathogenic element for a number of disorders. previous studies have reported that the -1031 t/c and -238 g/a polymorphisms in the promoter region of the tnf-α gene are important factors in reproductive-related disorders. one of the most common gynecological diseases of women during the reproductive years is end...
متن کاملTumor Necrosis Factor-Alpha Stimulates Hepatic Lipogenesis
The hyperlipidemia accompanying infection has been attributed to production of tumor necrosis factor. This cytokine inhibits adipose tissue lipoprotein lipase, which could decrease clearance of lipoproteins. Infections also increase hepatic lipogenesis. We now have demonstrated that tumor necrosis factor-alpha stimulates lipid synthesis in vivo. 2 h after administration of tumor necrosis factor...
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ژورنال
عنوان ژورنال: Cell Discovery
سال: 2020
ISSN: 2056-5968
DOI: 10.1038/s41421-020-0143-5